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Sustained In Vitro Expansion of Bone Progenitors Is Cell Density Dependent

1 Jan 2004

Abstract excerpt

Osteogenic cells are an integral part of the dynamic tissue-remodeling process in bone and are potential tools for tissue engineering and cell-based therapies. We examined the role of glucocorticoids and cell density in the expansion of primary rat calvaria cell populations and osteoprogenitor subpopulations in adherent cell culture. Osteoprogenitor response to dexamethasone (dex, a synthetic glucocorticoid known...

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PMID: 14688390
DOI: 10.1634/stemcells.22-1-39

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