Article
Differentiation of human bone marrow osteogenic stromal cells in vitro: induction of the osteoblast phenotype by dexamethasone.
Endocrinology - 1 Jan 1994
Cheng S L, Yang J W, Rifas L, Zhang S F, Avioli L V
Abstract excerpt
Human bone marrow stromal cells were examined for their osteogenic potential in an in vitro cell culture system. Dexamethasone (Dex) treatment induced morphological transformation of these cells from an elongated to a more cuboidal shape, increased their alkaline phosphatase activity and cAMP res...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alkaline Phosphatase
- Bone Marrow
- Bone Marrow Cells
- Calcification, Physiologic
- Cell Differentiation
- Cell Division
- Cells, Cultured
- Cyclic AMP
- Dexamethasone
- Female
- Humans
- Male
- Middle Aged
- Osteoblasts
- Osteocalcin