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Article

IGF2 gene variants and risk of hypertension in obese children and adolescents.

Pediatric research - 1 Apr 2010

Faienza Maria F, Santoro Nicola, Lauciello Rosaria, Calabrò Raffaele, Giordani Lucia, Di Salvo Giovanni, Ventura Annamaria, Delvecchio Maurizio, Perrone Laura, Del Giudice Emanuele M, Cavallo Luciano

Abstract excerpt

Obese children have a great risk of hypertension and cardiovascular morbidity in adults. The insulin-like growth factor type II (IGF-II) regulates glucose homeostasis, cardiovascular functions, and lipid metabolism. IGF2 gene variants have shown a strong association with weight, body mass index (BMI), and metabolic profile in adults. We performed the molecular screening of two IGF2 polymorphisms (6815 A/T, 820...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20057340
DOI: 10.1203/PDR.0b013e3181d22757

Genes

IGF2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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