Insulin and diastolic dysfunction in lean and obese hypertensives: genetic influence.

doi:10.1161/01.hyp.34.6.1208

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Article

Insulin and diastolic dysfunction in lean and obese hypertensives: genetic influence.

Hypertension (Dallas, Tex. : 1979) - 1 Dec 1999

Grandi A M, Zanzi P, Fachinetti A, Gaudio G, Ceriani L, Bertolini A, Guasti L, Venco A

Abstract excerpt

We investigated the influence of genetic predisposition to hypertension by studying the relation between insulin sensitivity and left ventricular (LV) mass and function in untreated lean and obese hypertensives. We selected 50 lean hypertensives with normotensive parents (negative family history of hypertension [F-]), 64 lean hypertensives with 1 or both parents hypertensive (positive family history of...

Topics

Adult
Analysis of Variance
Area Under Curve
Blood Glucose
Body Constitution
Body Mass Index
C-Peptide
Diastole
Echocardiography
Female
Genetic Predisposition to Disease
Glucose Tolerance Test
Heart Ventricles
Humans
Hypertension

Source

Open in PubMed

Identifiers

PMID: 10601120
DOI: 10.1161/01.hyp.34.6.1208

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Insulin

Male

Middle Aged