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Article

Insulin-Like Growth Factor-1 and Receptor Contribute Genetic Susceptibility to Hypertension in a Han Chinese Population.

American journal of hypertension - 10 Mar 2018

Yao Yingshui, Zhu Lijun, Fang Zhengmei, Yang Song, Chen Yanchun, Jin Yuelong, Zhao Xianghai, Zhao Hailong, Zhuang Qian, Chen Xiaotian, Shen Chong

Abstract excerpt

BACKGROUND: Insulin-like growth factor 1 (IGF-1) and IGF-1 receptor (IGF-1R) have been suggested to mediate the pathophysiological response to elevated blood pressure. This study aims to evaluate the association of IGF-1 and IGF-1R with hypertension. METHODS: Overall, 2,012 hypertensive cases and 2,210 controls were included in a case-control study, and 10 tagging single nucleotide polymorphisms (tagSNPs) were...

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PMID: 29126188
DOI: 10.1093/ajh/hpx195

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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