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Article

LSS rs2254524 Increases the Risk of Hypertension in Children and Adolescents with Obesity.

Genes - 13 Aug 2023

Umano Giuseppina Rosaria, Cirillo Grazia, Rondinelli Giulia, Sanchez Gianmaria, Marzuillo Pierluigi, Guarino Stefano, Di Sessa Anna, Papparella Alfonso, Miraglia Del Giudice Emanuele

Abstract excerpt

Childhood obesity and its related comorbidities have become major health issues over the last century. Among these comorbidities, cardiovascular diseases, especially hypertension, are the most significant. Recently, a polymorphism affecting the activity of lanosterol synthase has been associated with an increased risk of hypertension in adolescents. In this study, we aimed to investigate the effect of LSS...

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Identifiers

PMID: 37628669
DOI: 10.3390/genes14081618
PMCID: PMC10454860

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