Article
Association between birth weight, body mass index and IGF2/ApaI polymorphism.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society - 1 Oct 2005
Gomes M V M, Soares M R, Pasqualim-Neto A, Marcondes C R, Lôbo R B, Ramos E S
Abstract excerpt
Insulin-like growth factor II (IGF-II) is a polypeptide that plays a key role in mammalian growth, influencing fetal cell division, differentiation, and possibly metabolic regulation. In adult humans, polymorphisms of the IGF2 gene have been associated with predisposition to obesity. In the present study, we tested the association between IGF2/ApaI genotype and Body Mass Index (BMI) in 294 healthy volunteers (95...
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