Article
Genetic diversity on the integrase region of the pol gene among HIV type 1-infected patients naive for integrase inhibitors in São Paulo City, Brazil.
AIDS research and human retroviruses - 1 Jan 2010
Arruda Liã Bárbara, Fonseca Luiz Augusto M, Duarte Alberto J S, Casseb Jorge
Abstract excerpt
The presence of mutations associated with integrase inhibitor (INI) resistance among INI-naive patients may play an important clinical role in the use of those drugs Samples from 76 HIV-1-infected subjects naive to INIs were submitted to direct sequencing. No differences were found between naive (25%) subjects and subjects on HAART (75%). No primary mutation associated with raltegravir or elvitegravir resistance...
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