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Article

Integrase variability and susceptibility to HIV integrase inhibitors: impact of subtypes, antiretroviral experience and duration of HIV infection.

The Journal of antimicrobial chemotherapy - 1 Feb 2010

Garrido Carolina, Geretti Anna Maria, Zahonero Natalia, Booth Clare, Strang Angela, Soriano Vincent, De Mendoza Carmen

Abstract excerpt

BACKGROUND: Little is known about the extent and predictors of polymorphisms potentially influencing the susceptibility to HIV integrase inhibitors (INIs). METHODS: Genetic sequences of HIV integrase were obtained from INI-naive patients at two European clinics. The 39 amino acid changes at 29 integrase positions so far associated with INI resistance were examined according to HIV clade, prior antiretroviral...

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Source

Identifiers

PMID: 20007331
DOI: 10.1093/jac/dkp423

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Integrase variability and susceptibility to HIV integrase inhibitors: impact of subtypes, antiretroviral experience and duration of HIV infection.PMID 20007331Read ↗

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