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Article

Genetic diversity and naturally polymorphisms in HIV type 1 integrase isolates from Maputo, Mozambique: implications for integrase inhibitors.

AIDS research and human retroviruses - 1 Dec 2012

Oliveira Michelli F, Ramalho Dulce B, Abreu Celina M, Vubil Adolfo, Mabunda Nédio, Ismael Nalia, Francisco Cidia, Jani Ilesh V, Tanuri Amilcar

Abstract excerpt

HIV proviral DNA integration into the host chromosome is carried out by integrase becoming an important target antiretroviral therapy. Raltegravir was the first integrase inhibitor approved for use in HIV therapy and elvitegravir is in the late phase of clinical development; both show good result...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22497664
DOI: 10.1089/aid.2012.0058
PMCID: PMC3505052

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22497664-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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