Article
A role for the elongator complex in zygotic paternal genome demethylation.
Nature - 28 Jan 2010
Okada Yuki, Yamagata Kazuo, Hong Kwonho, Wakayama Teruhiko, Zhang Yi
Abstract excerpt
The life cycle of mammals begins when a sperm enters an egg. Immediately after fertilization, both the maternal and paternal genomes undergo dramatic reprogramming to prepare for the transition from germ cell to somatic cell transcription programs. One of the molecular events that takes place dur...
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