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Article

Genotype 1 and global hepatitis C T-cell vaccines designed to optimize coverage of genetic diversity.

The Journal of general virology - 1 May 2010

Yusim Karina, Fischer William, Yoon Hyejin, Thurmond James, Fenimore Paul W, Lauer Georg, Korber Bette, Kuiken Carla

Abstract excerpt

Immunological control of hepatitis C virus (HCV) is possible and is probably mediated by host T-cell responses, but the genetic diversity of the virus poses a major challenge to vaccine development. We considered monovalent and polyvalent candidates for an HCV vaccine, including natural, consensu...

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Source

Identifiers

PMID: 20053820
DOI: 10.1099/vir.0.017491-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20053820-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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