Article
Computational identification of a multi-peptide vaccine candidate in E2 glycoprotein against diverse Hepatitis C virus genotypes.
Journal of biomolecular structure & dynamics - 1 Dec 2023
Kumari Shweta, Kessel Amit, Singhal Divya, Kaur Gurpreet, Bern David, Lemay-St-Denis Claudèle, Singh Jasdeep, Jain Sahil
Abstract excerpt
Hepatitis C Virus (HCV) is estimated to affect nearly 180 million people worldwide, culminating in ∼0.7 million yearly casualties. However, a safe vaccine against HCV is not yet available. This study endeavored to identify a multi-genotypic, multi-epitopic, safe, and globally competent HCV vaccine candidate. We employed a consensus epitope prediction strategy to identify multi-epitopic peptides in all known...
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