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Article

Immunization with a synthetic consensus hepatitis C virus E2 glycoprotein ectodomain elicits virus-neutralizing antibodies.

Antiviral research - 1 Dec 2018

Tarr Alexander W, Backx Matthijs, Hamed Mohamed R, Urbanowicz Richard A, McClure C Patrick, Brown Richard J P, Ball Jonathan K

Abstract excerpt

Global eradication of hepatitis C virus (HCV) infection will require an efficacious vaccine capable of eliciting protective immunity against genetically diverse HCV strains. Natural spontaneous resolution of HCV infection is associated with production of broadly-neutralizing antibodies targeting the HCV glycoproteins E1 and E2. As such, production of cross-neutralizing antibodies is an important endpoint for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 30217650
DOI: 10.1016/j.antiviral.2018.09.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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