Article
The association between the -374T/A polymorphism of the receptor for advanced glycation endproducts gene and blood pressure and arterial stiffness is modified by glucose metabolism status: the Hoorn and CoDAM studies.
Journal of hypertension - 1 Feb 2010
Engelen Lian, Ferreira Isabel, Gaens Katrien H J, Henry Ronald M A, Dekker Jacqueline M, Nijpels Giel, Heine Robert J, 't Hart Leen M, van Greevenbroek Marleen M J, van der Kallen Carla J H, Blaak Ellen E, Feskens Edith J M, Ten Cate Hugo, Stehouwer Coen D A, Schalkwijk Casper G
Abstract excerpt
OBJECTIVES: Receptor for advanced glycation endproducts (RAGE)-ligand interaction may lead to vascular complications. Genetic variation in RAGE has been shown to alter expression, activity of RAGE or both. We, therefore, investigated whether RAGE single-nucleotide polymorphisms (SNPs) and haploty...
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