Article
Association of RAGE gene polymorphism with circulating AGEs level and paraoxonase activity in relation to macro-vascular complications in Indian type 2 diabetes mellitus patients.
Gene - 10 Sept 2013
Bansal Savita, Chawla Diwesh, Banerjee Basu Dev, Madhu Sri Venkata, Tripathi Ashok Kumar
Abstract excerpt
BACKGROUND AND AIMS: Sustained interaction of advanced glycation end products (AGEs) with their receptor RAGE and subsequent signaling plays an important role in the development of diabetic complications. Genetic variation of RAGE gene may be associated with the development of vascular complications in type 2 diabetes mellitus (T2DM). OBJECTIVES: The present study aimed to explore the possible association of RAGE...
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