Article
The -374A allele of the RAGE gene as a potential protective factor for vascular complications in type 2 diabetes: a meta-analysis.
The Tohoku journal of experimental medicine - 1 Apr 2010
Lu Weixin, Feng Bo
Abstract excerpt
The receptor for advanced glycation end products (RAGE) is a multi-ligand member of the immunoglobulin superfamily and may be involved in the development of diabetic vascular complications. The -374T/A polymorphism in the RAGE gene promoter has been suggested to affect gene transcription. However, the studies on the association between the -374T/A polymorphism and vascular complications in type 2 diabetes...
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