Article
Receptor for advanced glycation end products (RAGE) gene polymorphism and cardiovascular disease in end-stage renal disease patients.
Human immunology - 1 Nov 2015
Buraczynska Monika, Zaluska Wojciech, Buraczynska Kinga, Markowska-Gosik Dorota, Ksiazek Andrzej
Abstract excerpt
BACKGROUND/OBJECTIVES: Receptor for advanced glycation end products (RAGE) contributes to the pathogenesis of vascular and inflammatory diseases. We investigated whether the functional polymorphism in the promoter region of the RAGE gene (-374 T/A) influences development of cardiovascular disease in the end-stage renal disease (ESRD) patients. METHODS: The cohorts of 1866 ESRD patients and 1143 healthy subjects...
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