Article
Prediction of deleterious functional effects of non-synonymous single nucleotide polymorphisms in human nuclear receptor genes using a bioinformatics approach.
Drug metabolism letters - 1 Dec 2009
Liu Ya-He, Li Chun Guang, Zhou Shu-Feng
Abstract excerpt
The nuclear receptor (NR) superfamily represents an important group of regulating factors that control the expression of a number of target genes including those encoding important drug metabolizing enzymes and drug transporters. Single nucleotide polymorphism (SNP) is the most common mutation in...
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