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Article

Non-neutral nonsynonymous single nucleotide polymorphisms in human ABC transporters: the first comparison of six prediction methods.

Pharmacological reports : PR - 1 Jan 2011

Hao Da Cheng, Feng Yao, Xiao Rongrong, Xiao Pei Gen

Abstract excerpt

Nonsynonymous single nucleotide polymorphisms (nsSNPs) in coding regions that can lead to amino acid changes may cause alteration of protein function and account for susceptibility to disease and altered drug/xenobiotic response. Abundant nsSNPs have been found in genes coding for human ATP-binding cassette (ABC) transporters, but there is little known about the relationship between the genotype and phenotype of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22001980
DOI: 10.1016/s1734-1140(11)70608-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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