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Article

Phenotype prediction of non-synonymous single-nucleotide polymorphisms in human ATP-binding cassette transporter genes.

Basic & clinical pharmacology & toxicology - 1 Feb 2011

Wang Lin-Lin, Liu Ya-He, Meng Lu-Lu, Li Chun Guang, Zhou Shu-Feng

Abstract excerpt

A large number of non-synonymous single-nucleotide polymorphisms (nsSNPs) have been found in human genome, but there is poor knowledge on the relationship between the genotype and phenotype of these nsSNPs. Human ATP-binding cassette (ABC) transporters are able to transport a number of important substrates including endogenous and exogenous compounds. This study aimed to predict the phenotypical impact of nsSNPs...

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PMID: 20849526
DOI: 10.1111/j.1742-7843.2010.00627.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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