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Article

PINK1 function in health and disease.

EMBO molecular medicine - 1 Jun 2009

Deas Emma, Plun-Favreau Helene, Wood Nicholas W

Abstract excerpt

The role of mitochondria in sporadic Parkinson's disease (PD) has been debated for a little over 20 years since the description of complex I deficiency in the substantia nigra pars compacta (SNpc) of PD patients. However, the identification of recessive pathogenic mutations in the pink1 gene in familial PD cases firmly re-ignited interest in the pathophysiology of mitochondria in PD. PINK1 is a putative...

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Source

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Identifiers

PMID: 20049715
DOI: 10.1002/emmm.200900024
PMCID: PMC3378127

Genes

PINK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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