Article
Xenon blocks AMPA and NMDA receptor channels by different mechanisms.
Acta neurobiologiae experimentalis - 1 Jan 2009
Weigt Henry U, Fohr Karl J, Georgieff Michael, Georgieff Eva M, Senftleben Uwe, Adolph Oliver
Abstract excerpt
The noble gas xenon (Xe) inhibits not only NMDA receptors (NMDARs) but also the two other subtypes of glutamate receptor i.e. AMPA (AMPARs) and kainate receptors. Preliminary studies on AMPARs suggest that Xe sensitivity might be coupled to receptor desensitization. In order to find out if this h...
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