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Macrophage Mediated Immunomodulation During Cryptococcus Pulmonary Infection

24 Mar 2022

Abstract excerpt

Macrophages are key cellular components of innate immunity, acting as the first line of defense against pathogens to modulate homeostatic and inflammatory responses. They help clear pathogens and shape the T-cell response through the production of cytokines and chemokines. The facultative intracellular fungal pathogenCryptococcus neoformanshas developed a unique ability to interact with and manipulate host...

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PMID: 35402316
DOI: 10.3389/fcimb.2022.859049

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