Article
Variation in genes that regulate blood pressure are associated with glomerular filtration rate in Chinese.
PloS one - 1 Jan 2014
Montasser May E, Shimmin Lawrence C, Gu Dongfeng, Chen Jing, Gu Charles, Kelly Tanika N, Jaquish Cashell E, Rice Treva K, Rao Dabeeru C, Cao Jie, Chen Jichun, De-PeLiu, Whelton Paul K, Hamm Lotuce Lee, He Jiang, Hixson James E
Abstract excerpt
Chronic kidney disease (CKD) can be a consequence of diabetes, hypertension, immunologic disorders, and other exposures, as well as genetic factors that are still largely unknown. Glomerular filtration rate (GFR), which is widely used to measure kidney function, has a heritability ranging from 25% to 75%, but only 1.5% of this heritability is explained by genetic loci that have been identified to date. In this...
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