Article
Common variation at 1q24.1 (ALDH9A1) is a potential risk factor for renal cancer.
PloS one - 1 Jan 2015
Henrion Marc Y R, Purdue Mark P, Scelo Ghislaine, Broderick Peter, Frampton Matthew, Ritchie Alastair, Meade Angela, Li Peng, McKay James, Johansson Mattias, Lathrop Mark, Larkin James, Rothman Nathaniel, Wang Zhaoming, Chow Wong-Ho, Stevens Victoria L, Diver W Ryan, Albanes Demetrius, Virtamo Jarmo, Brennan Paul, Eisen Timothy, Chanock Stephen, Houlston Richard S
Abstract excerpt
So far six susceptibility loci for renal cell carcinoma (RCC) have been discovered by genome-wide association studies (GWAS). To identify additional RCC common risk loci, we performed a meta-analysis of published GWAS (totalling 2,215 cases and 8,566 controls of Western-European background) with imputation using 1000 Genomes Project and UK10K Project data as reference panels and followed up the most significant...
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