Identification of a 0.4 Kb deletion region in 10q26 associated with endometrial carcinoma.

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Article

Identification of a 0.4 Kb deletion region in 10q26 associated with endometrial carcinoma.

Oncology reports - 1 Feb 2010

Alves Margarida, Carreira Isabel, Liberato Paulo, Ramos Sância, Mafra Manuela, Inverno Alexandra S, Maia Ana T, Martins Ana Paula, Brito Miguel, Monteiro Carolino

Abstract excerpt

We have identified an allelic deletion common region in the q26 region of chromosome 10 in endometrial carcinomas, which has been reported previously as a potential target of genetic alterations related to this neoplasia. An allelotyping analysis of 19 pairs of tumoral and non-tumoral samples was accomplished using seven microsatellite polymorphic markers mapping in the 10q26 chromosomal region. Loss of...

Topics

Carcinoma
Chromosome Deletion
Chromosome Mapping
Chromosomes, Human, Pair 10
DNA Mutational Analysis
DNA Replication
Endometrial Neoplasms
Female
Genetic Linkage
Genotype
Humans
Loss of Heterozygosity
Matched-Pair Analysis
Microsatellite Instability

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Open in PubMed

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PMID: 20043116

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