Article
Genome-Wide Association Analysis of Protein-Coding Variants in IgA Nephropathy.
Journal of the American Society of Nephrology : JASN - 1 Nov 2023
Li Ming, Wang Yan-Na, Wang Ling, Meah Wee-Yang, Shi Dian-Chun, Heng Khai-Koon, Wang Li, Khor Chiea-Chuen, Bei Jin-Xin, Cheng Ching-Yu, Aung Tin, Liao Yun-Hua, Chen Qin-Kai, Gu Jie-Ruo, Kong Yao-Zhong, Lee Jimmy, Chong Siow-Ann, Subramaniam Mythily, Foo Jia-Nee, Cai Feng-Tao, Jiang Geng-Ru, Xu Gang, Wan Jian-Xin, Chen Meng-Hua, Yin Pei-Ran, Dong Xiu-Qing, Feng Shao-Zhen, Tang Xue-Qing, Zhong Zhong, Tan Eng-King, Chen Nan, Zhang Hong, Liu Zhi-Hong, Tai E Shyong, Liu Jian-Jun, Yu Xue-Qing
Abstract excerpt
SIGNIFICANCE STATEMENT: Genome-wide association studies have identified nearly 20 IgA nephropathy susceptibility loci. However, most nonsynonymous coding variants, particularly ones that occur rarely or at a low frequency, have not been well investigated. The authors performed a chip-based association study of IgA nephropathy in 8529 patients with the disorder and 23,224 controls. They identified a rare variant...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.