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Article

Genome-wide association analysis of high-density lipoprotein cholesterol in the population-based KORA study sheds new light on intergenic regions.

Circulation. Cardiovascular genetics - 1 Oct 2008

Heid Iris M, Boes Eva, Müller Martina, Kollerits Barbara, Lamina Claudia, Coassin Stefan, Gieger Christian, Döring Angela, Klopp Norman, Frikke-Schmidt Ruth, Tybjaerg-Hansen Anne, Brandstätter Anita, Luchner Andreas, Meitinger Thomas, Wichmann H-Erich, Kronenberg Florian

Abstract excerpt

BACKGROUND: High-density lipoprotein cholesterol (HDLC) is a strong risk factor for atherosclerosis and is assumed to be under considerable genetic control. We aimed to identify gene regions that influence HDLC levels by a genome-wide association analysis in the population-based KORA (Cooperative Health Research in the Region of Augsburg) study. METHODS AND RESULTS: In KORA S3/F3 (n=1643), we analyzed 377 865...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20031538
DOI: 10.1161/CIRCGENETICS.108.776708

Genes

CETP
LIPG
LPL

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