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Tandem repeat variation within and between species reveals signatures of selection in humans and chimpanzees

2026-01-21

Abstract excerpt

Tandem repeats (TRs) are highly mutable DNA elements that influence gene regulation 1 , protein structure 2 , and disease 3 . Until recently, their repetitive nature has hindered accurate TR sequencing and genotyping, resulting in sparse comparative data across species. In addition, we lack population-aware approaches to analyze TR conservation, divergence, and mutational dynamics. Here, leveraging telomere-to-...

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Literature Corpus work
bb861305-8f2a-5673-aacd-d3c42cbcfeb9
DOI
10.64898/2026.01.20.700717
Open publication

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Tandem repeat variation within and between species reveals signatures of selection in humans and chimpanzeesDOI 10.64898/2026.01.20.700717
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