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Article

Human SNP variability and mutation rate are higher in regions of high recombination.

Trends in genetics : TIG - 1 Jul 2002

Lercher Martin J, Hurst Laurence D

Abstract excerpt

Understanding the co-variation of nucleotide diversity and local recombination rates is important both for the mapping of disease-associated loci and in understanding the causes of sequence evolution. It is known that single nucleotide polymorphisms (SNPs) around protein coding genes show higher diversity in regions of high recombination. Here, we find that this correlation holds for SNPs across the entire human...

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Identifiers

PMID: 12127766
DOI: 10.1016/s0168-9525(02)02669-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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