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Article

Bases adjacent to mononucleotide repeats show an increased single nucleotide polymorphism frequency in the human genome.

Bioinformatics (Oxford, England) - 1 Apr 2011

Siddle K J, Goodship J A, Keavney B, Santibanez-Koref M F

Abstract excerpt

Mononucleotide repeats (MNRs) are abundant in eukaryotic genomes and exhibit a high degree of length variability due to insertion and deletion events. However, the relationship between these repeats and mutation rates in surrounding sequences has not been systematically investigated. We have analyzed the frequency of single nucleotide polymorphisms (SNPs) at positions close to and within MNRs in the human genome....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21317137
DOI: 10.1093/bioinformatics/btr067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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