A regulatory polymorphism at position -309 in PTPRCAP is associated with susceptibility to diffuse-type gastric cancer and gene expression.

doi:10.1593/neo.91132

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Article

A regulatory polymorphism at position -309 in PTPRCAP is associated with susceptibility to diffuse-type gastric cancer and gene expression.

Neoplasia (New York, N.Y.) - 1 Dec 2009

Ju Hyoungseok, Lim Byungho, Kim Minjin, Kim Yong Sung, Kim Woo Ho, Ihm Chunhwa, Noh Seung-Moo, Han Dong Soo, Yu Hang-Jong, Choi Bo Youl, Kang Changwon

Abstract excerpt

PTPRCAP (CD45-AP) is a positive regulator of protein tyrosine phosphatase PTPRC (CD45), which activates Src family kinases implicated in tumorigenesis. Single-nucleotide polymorphism (SNP) rs869736 located at position -309 of the PTPRCAP promoter was associated with susceptibility to diffuse-type gastric cancer in the current case-control study. The minor-allele homozygote was significantly associated with a...

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Identifiers

PMID: 20019842
DOI: 10.1593/neo.91132
PMCID: PMC2794515

Genes

PTPRCAP
PTPRC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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