IkappaBalpha polymorphism at promoter region (rs2233408) influences the susceptibility of gastric cancer in Chinese.

doi:10.1186/1471-230X-10-15

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Article

IkappaBalpha polymorphism at promoter region (rs2233408) influences the susceptibility of gastric cancer in Chinese.

BMC gastroenterology - 5 Feb 2010

Wang Shiyan, Tian Linwei, Zeng Zhirong, Zhang Mingdong, Wu Kaichun, Chen Minhu, Fan Daiming, Hu Pinjin, Sung Joseph J Y, Yu Jun

Abstract excerpt

BACKGROUND: Nuclear factor of kappa B inhibitor alpha (I kappaB alpha) protein is implicated in regulating a variety of cellular process from inflammation to tumorigenesis. The objective of this study was to investigate the susceptibility of rs2233408 T/C genotype in the promoter region of I kappaB alpha to gastric cancer and the association of this polymorphism with clinicopathologic variables in gastric cancer...

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Identifiers

PMID: 20132559
DOI: 10.1186/1471-230X-10-15
PMCID: PMC2829487

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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