Article
Does steric interference between splice sites block the splicing of a short c-src neuron-specific exon in non-neuronal cells?
Genes & development - 1 Mar 1991
Black D L
Abstract excerpt
The neuron-specific splicing of the mouse c-src N1 exon was analyzed. Model src genes, transiently expressed in HeLa and LA-N-5 neuroblastoma cells, were assayed for the insertion of the 18-nucleotide neuron-specific N1 exon into their product mRNA. The normal clone fails to use this exon in HeLa cells but inserts the exon into 50% of the mature mRNA in LA-N-5 cells. When the exon and flanking intron sequences...
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