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Article

An element in the 5' common exon of the NCAM alternative splicing unit interacts with SR proteins and modulates 5' splice site selection.

Nucleic acids research - 15 Jun 1999

Côté J, Simard M J, Chabot B

Abstract excerpt

The neural cell adhesion molecule (NCAM) gene contains an 801 nt exon that is included preferentially in neuronal cells. We have set up an in vitro splicing system that mimics the neuro-specific alternative splicing profile of NCAM exon 18. Splicing regulation is observed using model pre-mRNAs that contain competing 5' or 3' splice sites, suggesting that distinct pathways regulate NCAM 5' and 3' splice site...

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Identifiers

PMID: 10352182
DOI: 10.1093/nar/27.12.2529
PMCID: PMC148457

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Source receipt: pubmed, retrieved 7 Sept 2026.

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