Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Complexities and sequence similarities of mRNA populations of cholinergic (NS20-Y) and adrenergic (N1E-115) murine neuroblastoma cell lines.

Differentiation; research in biological diversity - 1 Jul 1990

Strauss W L

Abstract excerpt

The clonal murine neuroblastoma cell lines NS20-Y and N1E-115 have been proposed as models for examining the commitment of neural crest cells to either the cholinergic or adrenergic phenotype, respectively. The validity of this model depends in part on the extent to which these two cell lines have diverged as a result of their transformed, rather than neuronal properties. In order to quantitate differences in...

Topics

Animals
Base Sequence
Cell Division
DNA
Mice
Neural Crest
Neuroblastoma
Nucleic Acid Hybridization
Parasympathetic Nervous System
Phenotype
RNA, Messenger

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Homology, Nucleic Acid

Sympathetic Nervous System

Tumor Cells, Cultured

Source

Identifiers

PMID: 2253838
DOI: 10.1111/j.1432-0436.1990.tb00536.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2253838-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Complexities and sequence similarities of mRNA populations of cholinergic (NS20-Y) and adrenergic (N1E-115) murine neuroblastoma cell lines.PMID 2253838Read ↗

Gene structure of mammalian acetylcholinesterase. Alternative exons dictate tissue-specific expression.Semantic proximity Read ↗

Does steric interference between splice sites block the splicing of a short c-src neuron-specific exon in non-neuronal cells?Semantic proximity Read ↗

Expression of three alternative acetylcholinesterase messenger RNAs in human tumor cell lines of different tissue origins.Semantic proximity Read ↗

Compartmentalization of acetylcholinesterase mRNA and enzyme at the vertebrate neuromuscular junctionSemantic proximity Read ↗

Diversity of mRNA expression for muscarinic acetylcholine receptor subtypes and neuronal nicotinic acetylcholine receptor subunits in human mononuclear leukocytes and leukemic cell lines.Semantic proximity Read ↗

Differentiation of cholinergic neurons and physiological role of ciliary neurotrophic factor (CNTF).Semantic proximity Read ↗

Neuroblastoma plasticity during metastatic progression stems from the dynamics of an early sympathetic transcriptomic trajectorySemantic proximity Read ↗

Comparative Single-Cell Transcriptomics of Human Neuroblastoma and Preclinical Models Reveals Conservation of an Adrenergic Cell StateSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.