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Article

PTEN mutations and relationship to EGFR, ERBB2, KRAS, and TP53 mutations in non-small cell lung cancers.

Lung cancer (Amsterdam, Netherlands) - 1 Sept 2010

Jin Guang, Kim Min Jung, Jeon Hyo-Sung, Choi Jin Eun, Kim Dong Sun, Lee Eung Bae, Cha Sung Ick, Yoon Ghil Sook, Kim Chang Ho, Jung Tae Hoon, Park Jae Yong

Abstract excerpt

Somatic mutations of phosphatase and tensin homolog deleted on chromosome ten (PTEN) in non-small cell lung cancers (NSCLCs) have been investigated in but a small number of cases. In addition, the relationship between PTEN mutations and epidermal growth factor receptor (EGFR), KRAS, and TP53 mutations has not been investigated. Therefore, we investigated the frequency of PTEN mutations in 176 surgically resected...

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Identifiers

PMID: 20018398
DOI: 10.1016/j.lungcan.2009.11.012

Genes

PTEN
EGFR
KRAS
ERBB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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