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Tumor suppressor PTEN regulation by tobacco smoke in lung squamous-cell carcinoma based on bioinformatics analysis

1 Aug 2023

Abstract excerpt

Phosphatase and tensin homolog deleted on chromosome 10 (PTEN), is a tumor suppressor inactivated in a variety of human cancers. PTEN alteration correlates with lung squamous-cell carcinoma (LUSC) histology. However, it is still unclear how tobacco smoke regulates PTEN in LUSC tissues. In this study, we used free online databases and online tools to analyze PTEN expression and the role of smoking on PTEN...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37609416
DOI: 10.1016/j.heliyon.2023.e19044

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