Article
Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals.
Atherosclerosis - 1 Feb 2010
Heid Iris M, Henneman Peter, Hicks Andrew, Coassin Stefan, Winkler Thomas, Aulchenko Yurii S, Fuchsberger Christian, Song Kijoung, Hivert Marie-France, Waterworth Dawn M, Timpson Nicholas J, Richards J Brent, Perry John R B, Tanaka Toshiko, Amin Najaf, Kollerits Barbara, Pichler Irene, Oostra Ben A, Thorand Barbara, Frants Rune R, Illig Thomas, Dupuis Josée, Glaser Beate, Spector Tim, Guralnik Jack, Egan Josephine M, Florez Jose C, Evans David M, Soranzo Nicole, Bandinelli Stefania, Carlson Olga D, Frayling Timothy M, Burling Keith, Smith George Davey, Mooser Vincent, Ferrucci Luigi, Meigs James B, Vollenweider Peter, Dijk Ko Willems van, Pramstaller Peter, Kronenberg Florian, van Duijn Cornelia M
Abstract excerpt
OBJECTIVE: Plasma adiponectin is strongly associated with various components of metabolic syndrome, type 2 diabetes and cardiovascular outcomes. Concentrations are highly heritable and differ between men and women. We therefore aimed to investigate the genetics of plasma adiponectin in men and women. METHODS: We combined genome-wide association scans of three population-based studies including 4659 persons. For...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.