Article
The genetic basis of plasma variation in adiponectin, a global endophenotype for obesity and the metabolic syndrome.
The Journal of clinical endocrinology and metabolism - 1 Sept 2001
Comuzzie A G, Funahashi T, Sonnenberg G, Martin L J, Jacob H J, Black A E, Maas D, Takahashi M, Kihara S, Tanaka S, Matsuzawa Y, Blangero J, Cohen D, Kissebah A
Abstract excerpt
Here we present the first genetic analysis of adiponectin levels, a newly identified adipocyte-derived protein. Recent work has suggested that adiponectin may play a role in mediating the effects of body weight as a risk factor for coronary artery disease. For this analysis we assayed serum levels of adiponectin in 1100 adults of predominantly northern European ancestry distributed across 170 families....
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