Article
Genome-wide linkage and association analyses to identify genes influencing adiponectin levels: the GEMS Study.
Obesity (Silver Spring, Md.) - 1 Apr 2009
Ling Hua, Waterworth Dawn M, Stirnadel Heide A, Pollin Toni I, Barter Philip J, Kesäniemi Y Antero, Mahley Robert W, McPherson Ruth, Waeber Gérard, Bersot Thomas P, Cohen Jonathan C, Grundy Scott M, Mooser Vincent E, Mitchell Braxton D
Abstract excerpt
Adiponectin has a variety of metabolic effects on obesity, insulin sensitivity, and atherosclerosis. To identify genes influencing variation in plasma adiponectin levels, we performed genome-wide linkage and association scans of adiponectin in two cohorts of subjects recruited in the Genetic Epidemiology of Metabolic Syndrome Study. The genome-wide linkage scan was conducted in families of Turkish and southern...
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