Article
Clinical outcomes in non-small-cell lung cancer patients with EGFR mutations: pooled analysis.
Journal of cellular and molecular medicine - 1 Jan 2010
Paz-Ares Luis, Soulières Denis, Melezínek Ivan, Moecks Joachim, Keil Lorenz, Mok Tony, Rosell Rafael, Klughammer Barbara
Abstract excerpt
Non-small-cell lung cancer (NSCLC) with mutations in the epidermal growth factor receptor (EGFR) is a distinct subgroup of NSCLCs that is particularly responsive to EGFR tyrosine-kinase inhibitors (TKIs). A weighted pooled analysis of available studies was performed to evaluate clinical outcome in patients with EGFR-mutated NSCLC who were treated with chemotherapy or EGFR TKIs. Median progression-free survival...
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