Overall Survival Analysis and Characterization of an EGFR Mutated Non-Small Cell Lung Cancer (NSCLC) Population.

doi:10.1016/j.arbres.2017.07.012

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Article

Overall Survival Analysis and Characterization of an EGFR Mutated Non-Small Cell Lung Cancer (NSCLC) Population.

Archivos de bronconeumologia - 1 Jan 2018

Aguiar Filipa, Fernandes Gabriela, Queiroga Henrique, Machado José Carlos, Cirnes Luís, Souto Moura Conceição, Hespanhol Venceslau

Abstract excerpt

BACKGROUND: Patients with activating somatic mutations in the Epidermal Growth Factor Receptor (EGFR) have better clinical outcomes when treated with Tyrosine Kinase Inhibitors (TKI) over chemotherapy. However, the impact of the use of TKIs on overall survival outside clinical trials is not well established. OBJECTIVE: To characterize and analyze the overall survival of a Caucasian population with NSCLC and EGFR...

Topics

Aged
Carcinoma, Non-Small-Cell Lung
ErbB Receptors
Female
Humans
Lung Neoplasms
Male
Mutation
Protein Kinase Inhibitors
Retrospective Studies
Sex Factors
Smoking
Survival Analysis

Source

Open in PubMed

Identifiers

PMID: 29079040
DOI: 10.1016/j.arbres.2017.07.012

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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