Article
Impact of EGFR inhibitor in non-small cell lung cancer on progression-free and overall survival: a meta-analysis.
Journal of the National Cancer Institute - 1 May 2013
Lee Chee Khoon, Brown Chris, Gralla Richard J, Hirsh Vera, Thongprasert Sumitra, Tsai Chun-Ming, Tan Eng Huat, Ho James Chung-Man, Chu Da Tong, Zaatar Adel, Osorio Sanchez Jemela Anne, Vu Vu Van, Au Joseph Siu Kie, Inoue Akira, Lee Siow Ming, Gebski Val, Yang James Chih-Hsin
Abstract excerpt
BACKGROUND: The epidermal growth factor receptor (EGFR) signaling pathway is crucial for regulating tumorigenesis and cell survival and may be important in the development and progression of non-small cell lung cancer (NSCLC). We examined the impact of EGFR-tyrosine kinase inhibitors (TKIs) on progression-free survival (PFS) and overall survival (OS) in advanced NSCLC patients with and without EGFR mutations....
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