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Article

IL-15 receptor deletion results in circadian changes of locomotor and metabolic activity.

Journal of molecular neuroscience : MN - 1 Jun 2010

He Yi, Wu Xiaojun, Khan Reas S, Kastin Abba J, Cornelissen-Guillaume Germaine G, Hsuchou Hung, Robert Barry, Halberg Franz, Pan Weihong

Abstract excerpt

Interleukin-15 (IL-15) is a cytokine produced in the normal brain that acts on its specific receptor IL-15Ralpha and co-receptors IL-2Rbeta and IL-2Rgamma in neuronal cells. The functions of the cerebral IL-15 system, however, are not yet clear. To test the hypothesis that IL-15Ralpha regulates metabolic activity and body temperature, we quantified the specific metabolic phenotype of IL-15Ralpha knockout mice....

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Identifiers

PMID: 20012227
DOI: 10.1007/s12031-009-9319-z
PMCID: PMC3939616

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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