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Article

Cerebral interleukin-15 shows upregulation and beneficial effects in experimental autoimmune encephalomyelitis.

Journal of neuroimmunology - 1 Jun 2010

Wu Xiaojun, Pan Weihong, He Yi, Hsuchou Hung, Kastin Abba J

Abstract excerpt

Interleukin (IL)-15 can cross the blood-brain barrier to act on its specific brain receptor (IL15Ralpha) and co-receptors. The important roles of neuronal IL15 and IL15Ralpha in experimental autoimmune encephalomeylitis (EAE) are suggested by the upregulation of IL15Ralpha mRNA in different regions of the brain and spinal cord, and by double-labeling immunohistochemistry showing neuronal localization of IL15 and...

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Source

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Identifiers

PMID: 20430449
DOI: 10.1016/j.jneuroim.2010.04.001
PMCID: PMC2883030

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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