Article
Metabolic responses in the cortex and hippocampus induced by Il-15rα mutation.
Molecular omics - 31 Oct 2022
He Yi, Ge Lijun, Tong Fang, Zheng Peng, Yang Jian, Zhou Jingjing, Sun Zuoli, Wang Haixia, Yang Shun, Li Yifan, Yu Yuxin
Abstract excerpt
Significant inroads have been achieved in our understanding of neuropathology with the discovery of the crosstalk between the nervous and immune systems. In the neuro-immune crosstalk, interleukin-15 (IL-15) and its receptors are essential mediators. The IL-15 system has been found to act on peripheral metabolism, including glucose, lipid and energy homeostasis. Nevertheless, whether it promotes neuropsychiatric...
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