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Article

Topographically induced self-deformation of the nuclei of cells: dependence on cell type and proposed mechanisms.

Journal of materials science. Materials in medicine - 1 Mar 2010

Davidson Patricia M, Fromigué Olivia, Marie Pierre J, Hasirci Vasif, Reiter Günter, Anselme Karine

Abstract excerpt

Osteosarcoma-derived cell lines (SaOs-2, MG63) have recently been shown to deform their nucleus considerably in response to surface topography. Such a deformation had not been described previously. Here we present results on additional cell lines, including cancerous (OHS4, U2OS), immortalized (F/STRO-1(+)A and FHSO6) and healthy cells (HOP). The cancerous cells were found to deform extensively, the immortalized...

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Identifiers

PMID: 20012166
DOI: 10.1007/s10856-009-3950-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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