Article
Absence of an association between lumican promoter variants and high myopia in the Korean population.
Ophthalmic genetics - 1 Jan 2000
Park Shin Hae, Mok Jeewon, Joo Choun-Ki
Abstract excerpt
PURPOSE: To determine the association of single nucleotide polymorphisms (SNPs) in the promoter region of the lumican (LUM) gene with high myopic Korean patients. METHODS: Genomic DNA samples were obtained from 128 unrelated Korean patients with high myopia who had refractive errors ≤ -9.25 and axial lengths ≥ 26.5 mm in both eyes, and 235 control subjects. We investigated two promoter SNPs of the LUM gene....
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